Toru Yamashita Selected Research

Galantamine (Galanthamine)

6/2019	Acceleration of NLRP3 inflammasome by chronic cerebral hypoperfusion in Alzheimer's disease model mouse.
11/2017	Therapeutic effects of drug switching between acetylcholinesterase inhibitors in patients with Alzheimer's disease.
11/2017	Different clinical effect of four antidementia drugs for Alzheimer's disease patients depending on white matter severity.
10/2017	Comprehensive effects of galantamine and cilostazol combination therapy on patients with Alzheimer's disease with asymptomatic lacunar infarction.
4/2016	Cognitive and affective benefits of combination therapy with galantamine plus cognitive rehabilitation for Alzheimer's disease.
1/2015	Long-Term Efficacy of Galantamine in Alzheimer's Disease: The Okayama Galantamine Study (OGS).
1/2015	Clinical Benefits for Older Alzheimer's Disease Patients: Okayama Late Dementia Study (OLDS).

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Toru Yamashita Research Topics

Disease

46	Stroke (Strokes) 01/2024 - 07/2007
44	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2024 - 06/2005
40	Alzheimer Disease (Alzheimer's Disease) 03/2024 - 08/2011
31	Ischemic Stroke 03/2024 - 01/2009
27	Brain Ischemia (Cerebral Ischemia) 01/2024 - 06/2005
25	Infarction (Infarctions) 01/2023 - 06/2005
16	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 03/2024 - 08/2013
16	Dementia (Dementias) 01/2023 - 10/2014
12	Inflammation (Inflammations) 01/2023 - 01/2011
10	Ischemia 03/2024 - 07/2007
10	Cerebral Infarction 03/2024 - 07/2011
10	Cognitive Dysfunction 01/2024 - 10/2014
10	Hypertension (High Blood Pressure) 06/2015 - 03/2011
9	Atrial Fibrillation 01/2023 - 02/2002
9	Neuroinflammatory Diseases 12/2022 - 03/2015
9	Metabolic Syndrome (Dysmetabolic Syndrome X) 06/2015 - 01/2011
8	Atrophy 06/2021 - 01/2014
6	Neoplasms (Cancer) 12/2022 - 08/2010
6	Hypoxia (Hypoxemia) 06/2020 - 07/2010
5	Neurodegenerative Diseases (Neurodegenerative Disease) 03/2024 - 07/2012
5	Pathologic Constriction (Stenosis) 10/2019 - 01/2016
4	Parkinson Disease (Parkinson's Disease) 02/2017 - 01/2012
4	Brain Injuries (Brain Injury) 10/2016 - 06/2005
3	Encephalitis (Encephalitis, Rasmussen) 12/2023 - 01/2013
3	Infections 12/2023 - 03/2012
3	Muscle Weakness 01/2023 - 05/2018
3	Muscular Diseases (Myopathy) 01/2023 - 01/2018
3	Disease Progression 11/2020 - 07/2016
3	Frontotemporal Dementia (Semantic Dementia) 01/2020 - 10/2017
3	Parkinsonian Disorders (Parkinsonism) 08/2018 - 01/2013
3	Cerebral Hemorrhage 01/2017 - 01/2014
2	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 04/2024 - 02/2017
2	Gliosis 01/2024 - 01/2011

Drug/Important Bio-Agent (IBA)

23	Proteins (Proteins, Gene)FDA Link 01/2024 - 07/2010
21	Neuroprotective AgentsIBA 03/2024 - 08/2010
15	EdaravoneIBA 03/2024 - 04/2009
14	Amyloid (Amyloid Fibrils)IBA 12/2022 - 08/2011
11	Tissue Plasminogen Activator (Alteplase)FDA Link 10/2020 - 11/2010
10	Telmisartan (Micardis)FDA Link 06/2015 - 07/2014
8	Therapeutic UsesIBA 03/2024 - 01/2017
8	Free Radical ScavengersIBA 11/2023 - 04/2009
8	salicylhydroxamic acid (SHAM)IBA 05/2020 - 06/2005
7	Galantamine (Galanthamine)FDA LinkGeneric 06/2019 - 01/2015
6	CollagenIBA 01/2021 - 07/2011
6	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2020 - 01/2011
6	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 06/2016 - 05/2007
6	Amlodipine (Norvasc)FDA LinkGeneric 03/2013 - 10/2007
5	RivaroxabanIBA 01/2023 - 08/2014
5	Warfarin (Coumadin)FDA LinkGeneric 01/2022 - 01/2014
5	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2020 - 10/2014
5	4-hydroxy-2-nonenal (4-hydroxynonenal)IBA 11/2019 - 01/2011
5	ameroidIBA 10/2019 - 01/2016
5	LipidsIBA 01/2018 - 06/2012
5	Donepezil (Aricept)FDA LinkGeneric 11/2017 - 01/2015
5	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2016 - 11/2010
5	Atorvastatin (Lipitor)FDA Link 03/2013 - 01/2011
4	AntioxidantsIBA 03/2024 - 06/2017
4	InflammasomesIBA 01/2024 - 03/2015
4	Glucose (Dextrose)FDA LinkGeneric 12/2023 - 01/2015
4	Immunoglobulin G (IgG)IBA 12/2023 - 01/2017
4	Alprostadil (Muse)FDA LinkGeneric 01/2023 - 10/2020
4	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2021 - 10/2016
4	UbiquitinIBA 01/2021 - 10/2016
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2020 - 01/2011
4	Biomarkers (Surrogate Marker)IBA 01/2020 - 01/2015
4	SynucleinsIBA 10/2019 - 01/2012
4	Twendee XIBA 10/2019 - 06/2017
4	CalciumIBA 08/2018 - 10/2014
4	Advanced Glycation End ProductsIBA 08/2018 - 07/2014
4	Rivastigmine (Exelon)FDA LinkGeneric 11/2017 - 01/2015
4	Memantine (Namenda)FDA Link 11/2017 - 01/2015
4	Cilostazol (Pletal)FDA LinkGeneric 10/2017 - 06/2012
4	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 01/2016 - 01/2009
4	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 01/2016 - 07/2010
4	Matrix Metalloproteinases (MMPs)IBA 03/2015 - 08/2011
3	NucleotidesIBA 01/2024 - 11/2018
3	PlasmalogensIBA 01/2024 - 01/2021
3	AntibodiesIBA 12/2023 - 01/2018
3	3-nitrotyrosineIBA 01/2023 - 08/2018
3	TocovidIBA 12/2022 - 08/2018
3	InterleukinsIBA 07/2021 - 07/2005
3	Peptides (Polypeptides)IBA 01/2021 - 11/2019
3	Reactive Oxygen Species (Oxygen Radicals)IBA 08/2020 - 07/2011
3	DNA (Deoxyribonucleic Acid)IBA 12/2018 - 06/2012
3	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 01/2016 - 08/2010
3	Annexin A5IBA 01/2016 - 07/2010
3	AngiotensinsIBA 06/2015 - 11/2014
3	AcetylglucosamineIBA 06/2015 - 11/2014
3	Matrix Metalloproteinase 9 (Gelatinase B)IBA 06/2015 - 01/2011
3	Angiotensin II Type 1 Receptor BlockersIBA 04/2015 - 11/2014
3	Angiotensin Receptor AntagonistsIBA 03/2015 - 10/2014
3	Insulin ReceptorIBA 01/2015 - 12/2012
3	CholesterolIBA 10/2014 - 01/2012
3	BenzopyransIBA 08/2006 - 02/2002
3	NIP142IBA 08/2006 - 02/2002
2	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2024 - 07/2005
2	Sirtuin 1IBA 01/2024 - 03/2013

Therapy/Procedure

32	Therapeutics 03/2024 - 07/2007
11	Activities of Daily Living (ADL) 12/2019 - 06/2012
6	Transplantation 01/2023 - 07/2012